The upcoming webinar will focus on both plasmid DNA (pDNA) and mRNA manufacturing for clinical and commercial batches. It will begin with an overview of the RNA therapeutics market, followed by a detailed look at pDNA manufacturing, an essential raw material for mRNA and viral vector therapies. A generic manufacturing template will be presented to address key challenges such as high viscosity, shear sensitivity, and process impurities, along with relevant case studies. The session will then shift to the use of pDNA in mRNA production, highlighting the unique challenges of mRNA manufacturing, including the sensitivity of intermediates to temperature, mechanical stress, and nucleases. Recommendations for overcoming these challenges across in vitro transcription, purification, and formulation will also be discussed.

• Get an overview of the RNA based therapeutics market
• Learn plasmid DNA and mRNA manufacturing challenges and recommendations on purification process development
• Learn end to end plasmid and mRNA manufacturing process workflows commonly used in pharmaceutical industry

pDNA, mRNA

Registration online at http://tipa.or.th/tipa/register/